Article

Accounting for B cell behaviour and sampling bias yields a superior predictor of anti-PD-L1 response in bladder cancer

2021-03-04

Abstract excerpt

<h4>ABSTRACT</h4> Tumor-infiltrating B cells and intratumorally-produced immunoglobulins (IG) play important roles in the tumor microenvironment and response to immunotherapy 1–5 . IgG antibodies produced by intratumoral B cells may drive antibody-dependent cellular cytotoxicity (ADCC) and enhance antigen presentation by dendritic cells 6–8 . Furthermore, B cells are efficient antigen-specific antigen presenter...

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Literature Corpus work: c3ef1be0-72a4-569c-8f11-835dae57ef73
DOI: 10.1101/2021.03.04.433370

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