Article

Predicting immunotherapy response in advanced bladder cancer: a meta-analysis of six independent cohorts

2024-04-22

Abstract excerpt

<h4>ABSTRACT</h4> Advanced bladder cancer patients show very variable responses to immune checkpoint inhibitors (ICIs) and effective strategies to predict response are still lacking. Here we integrate mutation and gene expression data from 707 advanced bladder cancer patients treated with anti-PD-1/anti-PD-L1 to build highly accurate predictive models. We find that, in addition to tumor mutational burden (TMB), e...

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Literature Corpus work: 66320ac9-5fb0-5d21-a28e-88ffd89e944e
DOI: 10.1101/2024.04.18.589711

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