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IGHA1 and IGHG1 expression panel predicts anti-PD-L1 response in muscle-invasive bladder cancer

2024-04-11

Abstract excerpt

<title>Abstract</title> <p>Purpose B cells located in tertiary lymphoid structures (TLSs) may undergo clonal expansion, somatic hypermutation, isotype switching, and tumor-specific antibody production, suggesting that antibody-producing plasma cells may be involved in antitumor immunity. Methods This study used a combination of single-cell sequencing (5 samples from our center, and 4 samples from PRJNA662018) a...

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Literature Corpus work
1d27f031-87b8-5edb-af30-dbb60de63825
DOI
10.21203/rs.3.rs-4189881/v1
Open publication

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IGHA1 and IGHG1 expression panel predicts anti-PD-L1 response in muscle-invasive bladder cancerDOI 10.21203/rs.3.rs-4189881/v1
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