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Article

Intratumoral immunoglobulin isotypes predict survival in lung adenocarcinoma subtypes.

Journal for immunotherapy of cancer - 29 Oct 2019

Isaeva O I, Sharonov G V, Serebrovskaya E O, Turchaninova M A, Zaretsky A R, Shugay M, Chudakov D M

Abstract excerpt

BACKGROUND: The role of tumor-infiltrating B-cells (TIBs) and intratumorally-produced antibodies in cancer-immunity interactions essentially remains terra incognita. In particular, it remains unexplored how driver mutations could be associated with distinct TIBs signatures and their role in tumor microenvironment. METHODS: Here we analyzed associations of immunoglobulin isotypes and clonality with survival in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31665076
DOI: 10.1186/s40425-019-0747-1
PMCID: PMC6819482

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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