Article

The single-cell and spatial landscape of plasma cells in muscle-invasive bladder cancer

2023-09-13

Abstract excerpt

B cells in tertiary lymphoid structures (TLSs) may undergo clonal expansion, somatic hypermutation, isotype switching, and tumor-specific antibody production, suggesting that antibody-producing plasma cells may be involved in anti-tumor immunity. This study used a combination of single-cell sequencing and spatial transcriptome research methods to investigate the relationship between TLSs and the immunoglobulin rep...

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Literature Corpus work: 52c02fc7-4e5b-5aeb-afe7-ccb9aea6d5d8
DOI: 10.21203/rs.3.rs-3331238/v1

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