Article

Distinct features of human myeloid cell cytokine response profiles identify neutrophil activation by cytokines as a prognostic feature during tuberculosis and cancer1

2019-09-19

Abstract excerpt

<h4>ABSTRACT</h4> Myeloid cells are a vital component of innate immunity and comprise of monocytes, macrophages, dendritic cells and granulocytes. How myeloid cell lineage affects activation states in response to cytokines remains poorly understood. The cytokine environment and cellular infiltrate during an inflammatory response may contain prognostic features that could predict disease outcome. Here we analyzed...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c3d249c8-f707-57b6-8023-f98de8225320
DOI: 10.1101/775296

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Distinct features of human myeloid cell cytokine response profiles identify neutrophil activation by cytokines as a prognostic feature during tuberculosis and cancer1DOI 10.1101/775296Read

Neutrophil degranulation, NETosis and platelet degranulation pathway genes are co-induced in whole blood up to six months before tuberculosis diagnosisSemantic proximity Read

Cytokine-Induced Transcriptional Changes in Human Neutrophils Reveal Immune Regulatory PlasticitySemantic proximity Read

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosisSemantic proximity Read

A single-cell cytokine dictionary of human peripheral bloodSemantic proximity Read

Monocyte transcriptome signatures of inflammation and enhanced neutrophil recruitment characterize immunopathology in the blood of tuberculosis patientsSemantic proximity Read

A single-cell cytokine dictionary of human peripheral bloodSemantic proximity Read

Genome-Wide Expression Profiling Identifies Type 1 Interferon Response Pathways in Active TuberculosisSemantic proximity Read

Dissecting type I and II interferon impacts on human immune cells in disease by a cell type-specific interferon response atlasSemantic proximity Read

Human and murine neutrophils share core transcriptional programs in both homeostatic and inflamed contextsSemantic proximity Read

Dissecting Interferon-Induced Transcriptional Programs in Human Peripheral Blood CellsSemantic proximity Read

Single-cell profiling reveals distinct subsets of CD14+ monocytes drive blood immune signatures of active tuberculosisSemantic proximity Read