Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-Wide Expression Profiling Identifies Type 1 Interferon Response Pathways in Active Tuberculosis

21 Sept 2012

Abstract excerpt

Tuberculosis (TB), caused by Mycobacterium tuberculosis (M.tb), remains the leading cause of mortality from a single infectious agent. Each year around 9 million individuals newly develop active TB disease, and over 2 billion individuals are latently infected with M.tb worldwide, thus being at risk of developing TB reactivation disease later in life. The underlying mechanisms and pathways of protection against TB...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to interferon and immune responses
Share to Mycobacterium research and diagnosis
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23029268
DOI: 10.1371/journal.pone.0045839

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-Wide Expression Profiling Identifies Type 1 Interferon Response Pathways in Active TuberculosisPMID 23029268Read ↗

Type I Interferons in the Pathogenesis of Tuberculosis: Molecular Drivers and Immunological ConsequencesSemantic proximity Read ↗

Transcriptional Profiling of Human Peripheral Blood Mononuclear Cells Identifies Diagnostic Biomarkers That Distinguish Active and Latent TuberculosisSemantic proximity Read ↗

Whole transcriptome sequencing reveals neutrophils’ transcriptional landscape associated with active tuberculosisSemantic proximity Read ↗

Human gene expression profiles of susceptibility and resistance in tuberculosis.Semantic proximity Read ↗

Functional correlations of pathogenesis-driven gene expression signatures in tuberculosis.Semantic proximity Read ↗

Comprehensive identification of immuno-related transcriptional signature for active pulmonary tuberculosis by integrated analysis of array and single cell RNA-seqSemantic proximity Read ↗

A modular transcriptional signature identifies phenotypic heterogeneity of human tuberculosis infectionSemantic proximity Read ↗

Identification of immune biomarkers in recent active pulmonary tuberculosisSemantic proximity Read ↗

A 380-gene meta-signature of active tuberculosis compared with healthy controlsSemantic proximity Read ↗

Computational reassessment of RNA-seq data reveals key genes in active tuberculosisSemantic proximity Read ↗

Blood transcriptomics reveal the evolution and resolution of the immune response in tuberculosisSemantic proximity Read ↗

Transcriptional Profiling and Deriving a Seven-Gene Signature That Discriminates Active and Latent Tuberculosis: An Integrative Bioinformatics ApproachSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.