Article

Neuronal Lipoprotein Lipase Deficiency alters Neuronal Function and Hepatic Metabolism

2020-02-26

Abstract excerpt

<title>Abstract</title> <p>Background: The autonomic regulation of hepatic metabolism offers a novel target for the treatment of non-alcoholic fatty liver disease (NAFLD). However, the molecular characteristics of neurons that regulate the brain-liver axis remain unclear. Since mice lacking neuronal lipoprotein lipase (LPL) develop perturbations in neuronal lipid-sensing and systemic energy balance, we reasoned t...

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Literature Corpus work: c3ca71db-f5a5-580a-a45a-1ac238742ac2
DOI: 10.21203/rs.2.24553/v1

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