Article
Lipid sensing in the brain and regulation of energy balance.
Diabetes & metabolism - 1 Feb 2014
Moullé V-S, Picard A, Le Foll C, Levin B-E, Magnan C
Abstract excerpt
Nutrient-sensitive neurons [to glucose and fatty acids (FAs)] are present at many sites throughout the brain, including the hypothalamus and brain stem, and play a key role in the neural control of energy and glucose homoeostasis. Through their neuronal output, FAs can modulate feeding behaviour as well as insulin secretion and activity. Central administration of oleate, for example, inhibits food intake and...
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