Article

Mechanisms of DNA repair have evolved to minimise the probability of nonsense mutations

2021-06-22

Abstract excerpt

<h4>ABSTRACT</h4> Variation in sequence mutability has important implications for evolutionary models and predicting disease occurrence, and is driven in part by evolutionary divergence in mechanisms of DNA repair. The aim of this study was twofold: first, to assess the effect of local sequence context on substitution rates in the mouse lineage; second, to investigate the relationship between sequence mutability...

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Literature Corpus work: c3c418a3-5711-597e-9fe1-2b91e8e3890b
DOI: 10.1101/2021.06.22.449367

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