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Single Cell Transcriptomic Analysis of Spinal Ependymoma from a Patient with NF2-related Schwannomatosis Indicates a Radial-Glia to Ependymal Cell Developmental Hierarchy

2025-07-03

Abstract excerpt

Spinal ependymoma (SP-EPN) is a rare spinal cord tumor with no effective treatment. There is critical need to understand its cellular origins so disease models can be generated for drug development. Large-scale genomic studies may misrepresent rare cancer stem cell populations. We performed single-cell RNA-sequencing and spatial transcriptomics on a rare sample of SP-EPN from a patient with NF2-related Schwannomat...

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Literature Corpus work: c37c0690-9de1-52ea-a22f-4c2f11cb9949
DOI: 10.22541/au.175153904.47554285/v1

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