Article

Single-cell RNA Sequencing of Pediatric Ependymoma Unravels Subclonal Heterogeneity Associated with Patient Survival

2022-03-01

Abstract excerpt

Ependymoma (EPN) is a malignant glial tumor occurring throughout central nervous system which commonly presents in children. Although recent studies have characterized EPN samples at both the bulk and single-cell level, intra-tumoral heterogeneity across subclones remains a confounding factor which impedes understanding of EPN biology. In this study, we generated a high-resolution single-cell dataset of pediatric...

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Literature Corpus work: 696bd095-d296-5576-b12a-b3c55db47292
DOI: 10.1101/2022.02.26.482082

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Single-cell RNA Sequencing of Pediatric Ependymoma Unravels Subclonal Heterogeneity Associated with Patient SurvivalDOI 10.1101/2022.02.26.482082Read

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