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Article

Expression alterations define unique molecular characteristics of spinal ependymomas.

Oncotarget - 14 Aug 2015

Lourdusamy Anbarasu, Rahman Ruman, Grundy Richard G

Abstract excerpt

Ependymomas are glial tumors that originate in either intracranial or spinal regions. Although tumors from different regions are histologically similar, they are biologically distinct. We therefore sought to identify molecular characteristics of spinal ependymomas (SEPN) in order to better understand the disease biology of these tumors. Using gene expression profiles of 256 tumor samples, we identified increased...

Topics

Biomarkers, Tumor
Brain Neoplasms
Cellular Senescence
Chromosomes, Human, Pair 22
Cluster Analysis
Computational Biology
Databases, Genetic
Ependymoma
Gene Expression Profiling
Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Regulatory Networks

Genes, Neurofibromatosis 2

Genetic Predisposition to Disease

Humans

Oligonucleotide Array Sequence Analysis

Phenotype

Spinal Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 25909290
DOI: 10.18632/oncotarget.3715
PMCID: PMC4637320

Genes

BRD1
HDAC10
HIC2
HIRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Expression alterations define unique molecular characteristics of spinal ependymomas.PMID 25909290Read ↗

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