Article

SARS-CoV-2 Omicron boosting induces de novo B cell response in humans

2022-09-22

Abstract excerpt

The primary two-dose SARS-CoV-2 mRNA vaccine series are strongly immunogenic in humans, but the emergence of highly infectious variants necessitated additional doses of these vaccines and the development of new variant-derived ones 1–4 . SARS-CoV-2 booster immunizations in humans primarily recruit pre-existing memory B cells (MBCs) 5–9 . It remains unclear, however, whether the additional doses induce germinal c...

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Literature Corpus work: c36ff495-27a2-5197-9280-c0c92e2dbcc1
DOI: 10.1101/2022.09.22.509040

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