Article

Third dose COVID-19 mRNA vaccine enhances IgG4 isotype switching and recognition of Omicron subvariants by memory B cells after mRNA but not adenovirus priming

2023-09-18

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Booster vaccinations are recommended to improve protection against severe disease from SARS-CoV-2 infection. With primary vaccinations involving various adenoviral vector and mRNA-based formulations, it remains unclear if these differentially affect the immune response to booster doses. We here examined the effects of homologous (mRNA/mRNA) and heterologous (adenoviral vecto...

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Literature Corpus work: c5ced49c-5acf-5c4c-92f3-150833dab1eb
DOI: 10.1101/2023.09.15.557929

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