Article

<i>cis</i> -regulatory architecture of a short-range EGFR organizing center in the <i>Drosophila melanogaster</i> leg

2018-07-10

Abstract excerpt

We characterized the establishment of an Epidermal Growth Factor Receptor (EGFR) organizing center (EOC) during leg development in Drosophila melanogaster . Initial EGFR activation occurs in the center of leg discs by expression of the EGFR ligand Vn and the EGFR ligand-processing protease Rho, each through single enhancers, vnE and rhoE , that integrate inputs from Wg, Dpp, Dll and Sp1. Deletion of vnE and r...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c30ea541-3ca2-5da6-8123-5a39440ea586
DOI: 10.1101/366948

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

<i>cis</i> -regulatory architecture of a short-range EGFR organizing center in the <i>Drosophila melanogaster</i> legDOI 10.1101/366948Read

cis-regulatory architecture of a short-range EGFR organizing center in the Drosophila melanogaster leg.Semantic proximity Read

Leg patterning driven by proximal-distal interactions and EGFR signaling.Semantic proximity Read

The feedback regulator Nord controls Dpp/BMP signaling via extracellular interaction with Dally in the <i>Drosophila</i> wingSemantic proximity Read

Groucho restricts rhomboid expression and couples EGFR activation with R8 selection during Drosophila photoreceptor differentiation.Semantic proximity Read

Hippo pathway perturbation disrupts cell fate control in the <i>Drosophila</i> eyeSemantic proximity Read

Combinatorial effects on gene expression at the <i>Lbx1</i> / <i>Fgf8</i> locus resolve Split-Hand/Foot Malformation type 3Semantic proximity Read

<i>Rab11</i> is essential for <i>lgl</i> mediated JNK–Dpp signaling in dorsal closure and epithelial morphogenesis in <i>Drosophila</i>Semantic proximity Read

Human ERG Oncoprotein Represses <i>Chip/LDB1</i> LIM-Domain Binding Gene in <i>Drosophila</i>Semantic proximity Read

Temporal misexpression of <i>En1</i> during limb development causes distinct phenotypesSemantic proximity Read

Single-Cell Atlas of the <em>Drosophila</em> Leg Disc Identifies a Long Non-Coding RNA Associated with Distal Leg DevelopmentSemantic proximity Read

The phylogenetic functional conservation of <i>Drosophila</i> Seven-In-Absentia (SINA) E3 ligase and its two human paralogs, SIAH1 and SIAH2, in <i>Drosophila</i> eye developmentSemantic proximity Read

The Wnt co-receptor Arrow-LRP5/6 is required for Planar Cell Polarity establishment in <i>Drosophila</i>Semantic proximity Read