Article
Leg patterning driven by proximal-distal interactions and EGFR signaling.
Science (New York, N.Y.) - 12 Jul 2002
Galindo M I, Bishop S A, Greig S, Couso J P
Abstract excerpt
wingless and decapentaplegic signaling establishes the proximal-distal axis of Drosophila legs by activating the expression of genes such as Distalless and dachshund in broad proximal-distal domains during early leg development. However, here we show that wingless and decapentaplegic are not required throughout all of proximal-distal development. The tarsus, which has been proposed to be an ancestral structure,...
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