Article

Active Beta-Catenin (ABC) promotes an invasive phenotype in pediatric osteosarcoma

2024-10-08

Abstract excerpt

<title>Abstract</title> <p>Osteosarcoma (OS) is an aggressive primary bone malignancy with peak incidence in children and adolescents. Despite current multimodal treatments, there has been little change in overall survival outcomes in the last two decades. The canonical Wnt/β-catenin pathway is known to be a critical pathway in OS progression. To better understand the molecular basis of OS and potentially provide...

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Literature Corpus work: c3026b23-29e0-50f2-90fc-0f0db6adf530
DOI: 10.21203/rs.3.rs-4979798/v1

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