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Article

Cytoplasmic and/or nuclear accumulation of the beta-catenin protein is a frequent event in human osteosarcoma.

International journal of cancer - 1 Dec 2002

Haydon Rex C, Deyrup Andrea, Ishikawa Akira, Heck Robert, Jiang Wei, Zhou Lan, Feng Tao, King David, Cheng Hongwei, Breyer Benjamin, Peabody Terrance, Simon Michael A, Montag Anthony G, He Tong-Chuan

Abstract excerpt

The molecular events that precede the development of osteosarcoma, the most common primary malignancy of bone, are unclear, and concurrent molecular and genetic alterations associated with its pathogenesis have yet to be identified. Recent studies suggest that activation of beta-catenin signaling may play an important role in human tumorigenesis. To investigate the potential role of beta-catenin deregulation in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12402302
DOI: 10.1002/ijc.10719
PMCID: PMC4122310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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