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Article

Characterization of β-catenin expression in canine osteosarcoma.

Veterinary and comparative oncology - 1 Mar 2011

Stein T J, Holmes K E, Muthuswamy A, Thompson V, Huelsmeyer M K

Abstract excerpt

Osteosarcoma (OSA) is the most frequently occurring malignant primary bone tumour in dogs and children and arises from cells of the osteoblast lineage. Inappropriate Wnt signalling activity has been implicated in human OSA. Altered expression of β-catenin, an integral member of the Wnt signalling pathway, has been associated with numerous human cancers, including OSA. In this study, 30 of the 37 primary canine...

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Identifiers

PMID: 21303455
DOI: 10.1111/j.1476-5829.2010.00236.x
PMCID: PMC3099435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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