Article
BPSS1504, a cluster 1 type VI secretion gene, is involved in intracellular survival and virulence of Burkholderia pseudomallei.
Infection and immunity - 1 May 2014
Hopf Verena, Göhler André, Eske-Pogodda Kristin, Bast Antje, Steinmetz Ivo, Breitbach Katrin
Abstract excerpt
Burkholderia pseudomallei is a Gram-negative rod and the causative agent of melioidosis, an emerging infectious disease of tropical and subtropical areas worldwide. B. pseudomallei harbors a remarkable number of virulence factors, including six type VI secretion systems (T6SS). Using our previously described plaque assay screening system, we identified a B. pseudomallei transposon mutant defective in the BPSS1504...
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