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The Burkholderia Type VI Secretion System 5: Composition, Regulation and Role in Virulence

10 Jan 2019

Abstract excerpt

The soil saprophyte and Tier I select agent Burkholderia pseudomallei can cause rapidly fatal infections in humans and animals. The capability of switching to an intracellular life cycle during infection appears to be a decisive trait of B. pseudomallei for causing disease. B. pseudomallei harbors multiple type VI secretion systems (T6SSs) orthologs of which are present in the surrogate organism Burkholderia...

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PMID: 30687298
DOI: 10.3389/fmicb.2018.03339

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