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Autotransporters and Their Role in the Virulence of Burkholderia pseudomallei and Burkholderia mallei

1 Jan 2011

Abstract excerpt

Burkholderia pseudomallei and Burkholderia mallei are closely related Gram-negative bacteria responsible for the infectious diseases melioidosis and glanders, respectively. Autotransporters (ATs) comprise a large and diverse family of secreted and outer membrane proteins that includes virulence-associated invasins, adhesins, proteases, and actin-nucleating factors. The B. pseudomallei K96243 genome contains 11...

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PMID: 21811486
DOI: 10.3389/fmicb.2011.00151

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