Article
Oral insulin immunotherapy in children at risk for type 1 diabetes in a randomized trial
2020-06-14
Abstract excerpt
<h4>Background</h4> Oral administration of antigen can induce immunological tolerance. Insulin is a key autoantigen in childhood type 1 diabetes with insulin autoimmunity often appearing in the first years of life. Here, oral insulin was given as antigen-specific immunotherapy before the onset of autoimmunity in children from age 6 months to assess its safety and actions on immunity and the gut microbiome. <h4>Met...
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Identifiers and source
- Literature Corpus work
- c2cae874-5ec0-5ec0-94cb-f5b4cae28815
- DOI
- 10.1101/2020.06.12.20129189