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Article

Growth and development of islet autoimmunity and type 1 diabetes in children genetically at risk.

Diabetologia - 1 Apr 2021

Nucci Anita M, Virtanen Suvi M, Cuthbertson David, Ludvigsson Johnny, Einberg Ulle, Huot Celine, Castano Luis, Aschemeier Bärbel, Becker Dorothy J, Knip Mikael, Krischer Jeffrey P

Abstract excerpt

AIMS/HYPOTHESIS: We aimed to evaluate the relationship between childhood growth measures and risk of developing islet autoimmunity (IA) and type 1 diabetes in children with an affected first-degree relative and increased HLA-conferred risk. We hypothesised that being overweight or obese during childhood is associated with a greater risk of IA and type 1 diabetes. METHODS: Participants in a randomised infant...

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Adolescent Development
Autoimmunity
Child Development
Heredity
Islets of Langerhans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pediatric Obesity

Randomized Controlled Trials as Topic

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Identifiers

PMID: 33474583
DOI: 10.1007/s00125-020-05358-3
PMCID: PMC7940594

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