Article

Impact of Arg175His mutation on the dynamical patterns of full-length human p53 protein

2022-03-30

Abstract excerpt

p53, a tumor suppressor protein, is essential for preventing cancer development. Although individual domains of the human p53 have been well analyzed, no study has experimentally revealed a full-length structure of human wild-type p53 protein at atomistic level. The presence of all human p53 domains in one structure will help in showing the correlated interactions among these domains, thus, leading to enhance our...

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Literature Corpus work: c2a5b96b-8b20-5e70-a19a-e53d74ace2be
DOI: 10.22541/au.164864908.89492718/v1

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