Article

Novel extracellular role of REIC/Dkk-3 protein in PD-L1 regulation in cancer cells

2022-07-20

Abstract excerpt

<title>Abstract</title> <p>The adenovirus-REIC/Dkk-3 expression vector (Ad-REIC) is a clinical study's focus, with the goal of using this gene to exploit the quenching of several cancer types. <italic>REIC/DKK-</italic>3 gene's cancer-suppressing mechanisms depend on multiple pathways that exert both direct and indirect effects on cancers. The direct effect is triggered by REIC/Dkk-3-mediated ER-stress that cause...

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Literature Corpus work: c27aad20-1a29-58ff-9d6f-598ea5fe55db
DOI: 10.21203/rs.3.rs-1802365/v1

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