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Article

The Role of Oncogenes and Redox Signaling in the Regulation of PD-L1 in Cancer

2 Sept 2021

Abstract excerpt

Tumor cells can evade the immune system via multiple mechanisms, including the dysregulation of the immune checkpoint signaling. These signaling molecules are important factors that can either stimulate or inhibit tumor immune response. Under normal physiological conditions, the interaction between programmed cell death ligand 1 (PD-L1) and its receptor, programmed cell death 1 (PD-1), negatively regulates T cell...

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Identifiers

PMID: 34503236
DOI: 10.3390/cancers13174426

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