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Small Molecule Regulators of microRNAs Identified by High-Throughput Screen Coupled with High-Throughput Sequencing

2023-03-14

Abstract excerpt

<title>Abstract</title><p>MicroRNAs (miRNAs) regulate fundamental biological processes by silencing mRNA targets and are dysregulated in many diseases. Therefore, miRNA replacement or inhibition can be harnessed as potential therapeutics. However, existing strategies for miRNA modulation using oligonucleotides and gene therapies are challenging, especially for neurological diseases, and none have yet gained clinic...

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Literature Corpus work: c27896ee-d0a3-5c21-9628-7965f9580cb8
DOI: 10.21203/rs.3.rs-2617979/v1

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