Article
MicroRNAs: novel therapeutic targets in neurodegenerative diseases.
Drug discovery today - 1 Dec 2009
Roshan Reema, Ghosh Tanay, Scaria Vinod, Pillai Beena
Abstract excerpt
The prevalence of neurodegenerative disorders is rising steadily as human life expectancy increases. However, limited knowledge of the molecular basis of disease pathogenesis is a major hurdle in the identification of drug targets and development of therapeutic strategies for these largely incurable disorders. Recently, differential expression of endogenous regulatory small RNAs, known as 'microRNAs' (miRNAs), in...
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