Article

Autophagy in DG engrams mediates Rac1-dependent forgetting via TLR2/4 signals in microglia

2021-08-28

Abstract excerpt

<h4>BACKGROUND</h4> Engrams are considered to be substrates for memory storage, and the adaptive plasticity remolding that switch engrams to an inaccessible state cause forgetting. The normal function of engrams is ensured by the crosstalk between neurons and microglia, the major immune cells in the brain implicated in synapse remodeling and memory processing. However, the cellular processes and molecular mediato...

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Literature Corpus work: c22cc584-935d-599b-85a3-f8f751b49e99
DOI: 10.1101/2021.08.26.457763

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