Article

Remote memory engrams are controlled by encoding-specific tau phosphorylation

2023-12-03

Abstract excerpt

The engram represents the physical trace that encodes a specific memory and enables its recall 1–4 . Functional failure of the engram is linked to the progressive memory decline in Alzheimer’s disease 5 . However, it is unknown whether the microtubule-associated protein tau, a central factor in Alzheimer’s 6,7 , has a direct function in the engram. Here, we demonstrate that tau and encoding-associated tau phosp...

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Literature Corpus work: a4fa46ba-e502-50a0-a3b1-b0277f37aa2d
DOI: 10.1101/2023.12.01.569663

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