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Tag-and-Trigger: Basolateral Amygdala Stimulation Reinforces Behaviorally Tagged Hippocampus-Cortical Circuits to Enhance Memory Consolidation and Reverse Alzheimer's Disease Pathology in 5XFAD Mice

2026-07-29

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<title>Abstract</title> <p>Background Current Alzheimer’s disease (AD) therapies focused on amyloid-β (Aβ) clearance have yielded limited memory improvement, while deep brain stimulation (DBS) of memory-related nodes has produced inconsistent clinical outcomes. These shortcomings highlight an urgent need for interventions that target the breakdown of neural plasticity with circuit and temporal specificity. Metho...

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Literature Corpus work
626c50e1-9c00-5c59-954c-431bb0aa836b
DOI
10.21203/rs.3.rs-10245599/v1
Open publication

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Tag-and-Trigger: Basolateral Amygdala Stimulation Reinforces Behaviorally Tagged Hippocampus-Cortical Circuits to Enhance Memory Consolidation and Reverse Alzheimer's Disease Pathology in 5XFAD MiceDOI 10.21203/rs.3.rs-10245599/v1
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