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Repurposing Live Attenuated Trivalent MMR Vaccine as Cost-effective Cancer Immunotherapy

2022-03-01

Abstract excerpt

<h4>ABSTRACT</h4> Despite its rising promise, cancer immunotherapy remains out of reach for many patients because of the extensive cost of manufacturing immunotherapy products. In this study, we show that intratumoral injections of the trivalent measles, mumps, and rubella (MMR) live attenuated viral vaccine (LAVs) modulates a potent cytotoxic T-cell antitumor immune response, resulting in tumor growth inhibition...

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Identifiers and source

Literature Corpus work
c22c5717-35fb-579b-8c50-805b6030d333
DOI
10.1101/2022.02.25.481685
Open publication

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Repurposing Live Attenuated Trivalent MMR Vaccine as Cost-effective Cancer ImmunotherapyDOI 10.1101/2022.02.25.481685
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