Article

MEK / ERK inhibitor effectively impact generalized lymphatic anomaly (GLA) cells growth through EGFR / MEK /ERK signaling pathway

2020-03-10

Abstract excerpt

<title>Abstract</title> <p>Background Generalized lymphatic anomaly is characterized by diffuse or multicentric proliferation of dilated lymphatic vessels resembling common lymphatic malformation. Studies on GLA are frequently hampered by a lack of appropriate models to test the effects of potential treatments or decipher the mechanism of pathology. Moreover, diverse phenotypes observed with GLA require a large n...

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Literature Corpus work: c21fc5bb-eb53-50e8-8505-288f19c6f04c
DOI: 10.21203/rs.3.rs-16567/v1

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