Article

Single-cell RNA sequencing reveals cellular and molecular landscape of fetal cystic hygroma

2023-07-19

Abstract excerpt

<title>Abstract</title> <p>Background The molecular mechanism of fetal cystic hygroma (CH) is still unclear, and no study has previously reported the transcriptome changes of single cells in CH. In this study, single-cell transcriptome sequencing (scRNA-seq) was used to investigate the characteristics of cell subsets in the lesion tissues of CH patients. Methods The lesions of CH patients and controls were coll...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 59c4c820-3d18-5c76-a31c-2aea35d99dbc
DOI: 10.21203/rs.3.rs-3114234/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Single-cell RNA sequencing reveals cellular and molecular landscape of fetal cystic hygromaDOI 10.21203/rs.3.rs-3114234/v1Read

Decoding the molecular landscape of keloids: new insights from single-cell transcriptomicsSemantic proximity Read

Single-Cell RNA Sequencing Reveals Heterogeneity and Functional Diversity of Lymphatic Endothelial CellsSemantic proximity Read

Decoding Lymphangioleiomyomatosis (LAM) Niche Environment via Integrative Analysis of Single Cell Multiomics and Spatial TranscriptomicsSemantic proximity Read

Investigation into the genetics of fetal congenital lymphatic anomaliesSemantic proximity Read

A novel nonsense variant of the KAT6B gene associated with cystic hygroma in fetusSemantic proximity Read

Genetic etiology and obstetric outcome analysis of fetal cystic hygroma in a single-center studySemantic proximity Read

Single Cell Multiomics Identifies Cells and Genetic Networks Underlying Alveolar Capillary DysplasiaSemantic proximity Read

Haploinsufficiencies of FOXF1, FOXC2 and FOXL1 genes originated from deleted 16q24.1q24.2 fragment related with alveolar capillary dysplasia with misalignment of pulmonary veins and lymphedema–distichiasis syndrome: relationship to phenotypeSemantic proximity Read

Roles for RERE in lymphatic endothelial cell proliferation and survival, and human cystic lymphatic malformationsSemantic proximity Read

Genetic and Molecular Determinants of Lymphatic Malformations: Potential Targets for TherapySemantic proximity Read

Single-Cell Transcriptomic Analysis of Kaposi SarcomaSemantic proximity Read

NRAS mutation in a central conducting lymphatic anomaly and PPFIBP1::ROS1 fusion in a Gorham-stout disease patient.Semantic proximity Read