Article

Synthetic Growth Hormone-Releasing Hormone Agonist as Novel Treatment for Heart Failure with Preserved Ejection Fraction

2020-02-28

Abstract excerpt

<h4>Objective</h4> To test the hypothesis that the activation of the growth hormone-releasing hormone (GHRH) receptor signaling pathway within the myocardium both prevents and reverses heart failure with preserved ejection fraction (HFpEF). <h4>Background</h4> HFpEF is characterized by impaired myocardial relaxation, fibrosis and ventricular stiffness. Despite the rapidly increasing prevalence of HFpEF, no effec...

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Literature Corpus work: c20aedb8-8149-54df-9e4c-bd9531b284c9
DOI: 10.1101/2020.02.28.967000

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