Article

A Predictive Autoantibody Signature in Multiple Sclerosis

2023-05-02

Abstract excerpt

Although B cells are implicated in multiple sclerosis (MS) pathophysiology, a predictive or diagnostic autoantibody remains elusive. Here, the Department of Defense Serum Repository (DoDSR), a cohort of over 10 million individuals, was used to generate whole-proteome autoantibody profiles of hundreds of patients with MS (PwMS) years before and subsequently after MS onset. This analysis defines a unique cluster of...

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Literature Corpus work: 8a2e9cf9-c460-598b-b909-4ef7c222bccf
DOI: 10.1101/2023.05.01.23288943

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