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Deficient thalamo-cortical networks dynamics and sleep homeostatic processes in a redox dysregulation model relevant to schizophrenia

2021-07-20

Abstract excerpt

A growing body of evidence implicates thalamo-cortical oscillations with the neuropathophysiology of schizophrenia (SZ) in both mice and humans. Yet, the precise mechanisms underlying sleep perturbations in SZ remain unclear. Here, we characterised the dynamics of thalamo-cortical networks across sleep-wake states in a mouse model carrying a mutation in the enzyme glutathione synthetase gene (Gclm-/-) associated w...

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Literature Corpus work
c1cf4e5a-3f2a-5588-bbbd-353319ceb999
DOI
10.1101/2021.07.20.453026
Open publication

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Deficient thalamo-cortical networks dynamics and sleep homeostatic processes in a redox dysregulation model relevant to schizophreniaDOI 10.1101/2021.07.20.453026
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