Article

Thalamic control of sensory enhancement and sleep spindle properties in a biophysical model of thalamoreticular microcircuitry

2022-03-02

Abstract excerpt

Thalamoreticular circuitry is known to play a key role in attention, cognition and the generation of sleep spindles, and is implicated in numerous brain disorders, but the cellular and synaptic mechanisms remain intractable. Therefore, we developed the first detailed computational model of mouse thalamus and thalamic reticular nucleus microcircuitry that captures morphological and biophysical properties of ∼14,000...

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Literature Corpus work: b4c09d4e-a16c-5d42-8ffd-1854cbcb8f94
DOI: 10.1101/2022.02.28.482273

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