Article

Eukaryotic Translation Initiation Factor Loaded Extracellular Vesicles Promotes Macrophage Cholesterol Metabolism in ovarian cancer

2024-12-11

Abstract excerpt

<h4>Summary</h4> Tumor-driven immune suppression poses a significant impediment to the success of immunotherapy in ovarian cancer. Among the various mechanisms contributing to immune suppression, intracellular communication facilitated by tumor-derived extracellular vesicles (EVs) within the tumor microenvironment (TME) emerges as a pivotal factor influencing tumor growth. We discovered that EVs from both ovarian...

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Literature Corpus work: c1c892f7-5c65-548a-aa15-c32bd2210298
DOI: 10.1101/2024.12.06.627180

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