Article

Peanut oral immunotherapy differentially suppresses clonally distinct subsets of T helper cells

2021-08-01

Abstract excerpt

Food allergy affects an estimated 8% of children in the US, with increasing severity and global prevalence 1 . Oral immunotherapy (OIT) is a recently approved treatment with outcomes ranging from sustained tolerance to food allergen to no apparent benefit 2,3 . The immunological underpinnings that influence clinical outcomes of OIT still remain largely unresolved. Using single-cell RNA sequencing and paired TCRα/β...

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Literature Corpus work: c1c4cc48-e289-5879-96fb-4bf4a0f81b00
DOI: 10.1101/2021.07.29.21261049

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