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Article

Integrative transcriptomic analysis reveals key drivers of acute peanut allergic reactions

29 Nov 2017

Abstract excerpt

Abstract Mechanisms driving acute food allergic reactions have not been fully characterized. We profile the dynamic transcriptome of acute peanut allergic reactions using serial peripheral blood samples obtained from 19 children before, during, and after randomized, double-blind, placebo-controlled oral challenges to peanut. We identify genes with changes in expression triggered by peanut, but not placebo, during...

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Share to Allergic Rhinitis and Sensitization
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PMID: 29203772
DOI: 10.1038/s41467-017-02188-7

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