Article
High-dimensional immune profiles correlate with phenotypes of peanut allergy during food-allergic reactions.
Allergy - 1 Apr 2023
Klueber Julia, Czolk Rebecca, Codreanu-Morel Françoise, Montamat Guillem, Revets Dominique, Konstantinou Maria, Cosma Antonio, Hunewald Oliver, Skov Per Stahl, Ammerlaan Wim, Hilger Christiane, Bindslev-Jensen Carsten, Ollert Markus, Kuehn Annette
Abstract excerpt
BACKGROUND: Food challenges carry a burden of safety, effort and resources. Clinical reactivity and presentation, such as thresholds and symptoms, are considered challenging to predict ex vivo. AIMS: To identify changes of peripheral immune signatures during oral food challenges (OFC) that correlate with the clinical outcome in patients with peanut allergy (PA). METHODS: Children with a positive (OFC+ , n = 16)...
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