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Allergen recognition by specific effector Th2 cells enables IL-2-dependent activation of regulatory T cell responses in humans

2022-05-17

Abstract excerpt

Type 2 allergen-specific T cells are essential for the induction and maintenance of allergies to foods, and Tregs specific for these allergens are assumed to be involved in their resolution. However, it has not been convincingly demonstrated whether allergen-specific Treg responses are responsible for the generation of oral tolerance in humans. We observed that sustained food allergen exposure in the form of oral...

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Literature Corpus work
a2e91ffe-9589-51c5-aff1-1f4a28b3b022
DOI
10.1101/2022.05.17.22275017
Open publication

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Allergen recognition by specific effector Th2 cells enables IL-2-dependent activation of regulatory T cell responses in humansDOI 10.1101/2022.05.17.22275017
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