Back to search

Article

CSTA: A Biomarker Regulating Esophageal Stricture Epithelial Barrier, Potential Medication Target

2023-10-25

Abstract excerpt

Esophageal strictures resulting from ESD/EMR in the esophagus are distressing, with uncertain causes and treatments due to epithelial barrier dysfunction. We explored cystatin A (CSTA) as a novel biomarker for the esophageal epithelial barrier. CSTA regulates the barrier and is influenced by tacrolimus (FK506). Analyzing biopsy samples by proteomics, we identified CSTA as an esophageal epithelial biomarker. Knocki...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
c19fd858-d1b5-5881-821e-4793a5857ee0
DOI
10.1101/2023.10.23.563568
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 10 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
CSTA: A Biomarker Regulating Esophageal Stricture Epithelial Barrier, Potential Medication TargetDOI 10.1101/2023.10.23.563568
Cystatin SN promotes epithelial-mesenchymal transition and serves as a prognostic biomarker in lung adenocarcinomaSemantic proximity
Octreotide may improve pharyngocutaneous fistula healing through downregulation of cystatins: a pilot studySemantic proximity
Epithelial CST1 Promotes Airway Eosinophilic Inflammation in Asthma via the AKT Signaling PathwaySemantic proximity
Tight junction proteins in gastrointestinal and liver diseaseSemantic proximity
Modulation of cystatin A expression in human airway epithelium related to genotype, smoking, COPD, and lung cancer.Semantic proximity
Loss-of-function mutations in CST6 cause dry skin, desquamation and abnormal keratosis without hypotrichosis.Semantic proximity
Salivary (SD-type) cystatins: over one billion years in the making--but to what purpose?Semantic proximity
Expression of Type 2 Cystatin Genes <i>CST1-CST5</i> in Adult Human Tissues and the Developing Submandibular GlandSemantic proximity
Catestatin regulates the colonic mucus layer in inflammatory bowel diseaseSemantic proximity
Establishment of a CRISPR/Cas9-Mediated Cysltr1 Knockout Mouse Model and iTRAQ-Based Proteomic Analysis.Semantic proximity
Select a neighboring publication to make it the new centre.