Article
Expression of Type 2 Cystatin Genes <i>CST1-CST5</i> in Adult Human Tissues and the Developing Submandibular Gland
1 Jan 2002
Abstract excerpt
Type 2 cystatins comprise a class of cysteine peptidase inhibitor presumed to mediate protective functions at various locations, including the oral cavity. Seven cystatin genes are clustered within a 300-kb region of human 20p11.2. "Salivary" cystatins, encoded by CST1, 2, 4, and 5, are present in saliva at significant levels but have also been reported in other secretions, such as tears, suggesting that during...
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