Article
Salivary (SD-type) cystatins: over one billion years in the making--but to what purpose?
Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists - 1 Jan 2002
Dickinson D P
Abstract excerpt
Human saliva contains relatively abundant proteins that are related ancestrally in sequence to the cystatin superfamily. Most, although not all, members of this superfamily are potent inhibitors of cysteine peptidases. Four related genes have been identified, CST1, 2, 4 and 5, encoding cystatins SN, SA, S, and D, respectively. CST1, 4, and probably CST5 are now known to be expressed in a limited number of other...
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