Article

Octreotide may improve pharyngocutaneous fistula healing through downregulation of cystatins: a pilot study

2022-04-27

Abstract excerpt

<h4>Objective</h4> Pharyngocutaneous fistula (PCF) and salivary leaks are well known complications of head and neck surgery. The medical management of PCF has included the use of octreotide without a well-defined understanding of its therapeutic mechanism. We hypothesized that octreotide induces alterations in the saliva proteome and that these alterations may provide insight into the mechanism of action underlyin...

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Literature Corpus work: 148db473-3d8b-54d4-9d82-6b314d53140c
DOI: 10.1101/2022.04.24.22273652

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