Article

CCDC113 stabilizes sperm axoneme and head-tail coupling apparatus to ensure male fertility

2024-04-14

Abstract excerpt

The structural integrity of the sperm is crucial for male fertility, defects in sperm head-tail linkage and flagellar axoneme are associated with acephalic spermatozoa syndrome (ASS) and the multiple morphological abnormalities of the sperm flagella (MMAF). Notably, impaired head-tail coupling apparatus (HTCA) often accompanies defects in the flagellum structure, however, the molecular mechanisms underlying this p...

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Literature Corpus work: c1753e58-a511-5852-b2c1-d9b49d5b7f18
DOI: 10.1101/2024.04.12.589289

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